Taken together, these data demonstrated that activation of STAT3 and mTOR pathways are required for butyrate induction of Blimp-1 and, consequently, IL-10 production in Th1 cells.
Altogether, these two studies demonstrated that activation of SIRT1 can at least partially prevent lipid-induced decrease in β-cell function in vivo.
These studies demonstrated that activation of NOTCH1 specifically induces loss of the repressive mark Lys27 trimethylation of histone 3 (H3K27me3 4 by antagonizing the activity of PRC2.
Previously, it was demonstrated that activation of AhR protects against colitis41,53 and AhR−/− mice develop severe colitis compared to wild type mice and display increased inflammatory mediators54.
They demonstrated that activation of orexin neurons contributes to cardiovascular responses to forms of stress or arousal that are associated with a high level of attention to the surrounding environment, such as exploration (novelty) and conditioned fear.
Recently, it was demonstrated that activation of hypoxia-inducible factor-1α (Hif-1α) improves cell functions of progenitor cells of mesenchymal and endothelial origin.
Human imaging studies have demonstrated that activation of frontal and parietal cortical areas, mostly in the right hemisphere, are associated with sustained attention performance.
These results demonstrated that activation of AR in the MePD plays a critical role in the expression of the preference for estrous odors over male odors.
Fan et al. demonstrated that activation of the EGF receptor in mammary cells caused the activation of Yap [109].
We had previously demonstrated that activation of the brain microvasculature is an early event in an animal model of sepsis.
Overall, the metabolomic analyses demonstrated that activation of the TCA cycle and increased ATP generation are critical parameters for electricity generation by microflora.
