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Like other demonstrated targets of Ypk1 (e.g. Orm1, Orm2, Lac1, Lag1), Fps1 is a polytopic integral membrane protein.
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"They have shown their competence through demonstrated target practice.
These nanoparticles demonstrated target specific delivery in human lung cancer cells (which overexpress CD44 receptors).
Winer et al. have recently demonstrated targeting of F3-conjugated cisplatin-hydrogel nanoparticles to the vessels of various tumor xenografts [16].
We monitored tumor growth using high-frequency ultrasonography and demonstrated targeting specificity and kinetics of the NPs via in vivo fluorescent reflectance imaging.
Using MECA79 conjugation, we have demonstrated targeted delivery of tacrolimus to the lymph nodes following systemic administration, with the capacity for immune modulation in vivo.
Anti-Tn-MUC1 CAR T cells demonstrated target-specific cytotoxicity and successfully controlled tumor growth in xenograft models of T cell leukemia and pancreatic cancer.
They caused DNA mutation through cytidine (dC) deamination and demonstrated target sequence specificity.
Synovial microarray analysis demonstrated targeting of citrullinated fibrinogen in RA [ 20].
We demonstrated target expression of FAP in all subtypes of MPM.
VEGF121/rGel demonstrated targeted toxicity even after a one-hour exposure, with an IC50 of 5 nM.
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