Sentence examples for demonstrated targeted from inspiring English sources

Using MECA79 conjugation, we have demonstrated targeted delivery of tacrolimus to the lymph nodes following systemic administration, with the capacity for immune modulation in vivo.

We demonstrated targeted transposition into endogenous matrix attachment regions (MARs) and a chromosomally integrated tetracycline response element (TRE) in cultured human cells, using targeting proteins that bind to the transposon DNA.

In this regard, Hedley and colleagues genetically incorporated a cytoplasmically stable scFv into an artificial knob-deleted Ad fiber and demonstrated targeted gene transfer in vitro to cells expressing an artificial receptor containing the scFv epitope [15].

VEGF121/rGel demonstrated targeted toxicity even after a one-hour exposure, with an IC50 of 5 nM.

We demonstrated targeted insertion and inversion methods in the BGM system to add to its repertoire of genetic modification approaches.

We successfully demonstrated targeted deletions, inversions, and duplications of multiple gene clusters as well as large chromosomal deletions exceeding 9 Mb.

Winer et al. have recently demonstrated targeting of F3-conjugated cisplatin-hydrogel nanoparticles to the vessels of various tumor xenografts [16].

We monitored tumor growth using high-frequency ultrasonography and demonstrated targeting specificity and kinetics of the NPs via in vivo fluorescent reflectance imaging.

Synovial microarray analysis demonstrated targeting of citrullinated fibrinogen in RA [ 20].

As previously demonstrated, targeting multiple pathways is likely to be more efficacious for eradicating tumor cells than targeting EGFR alone (Müller et al., 2014).

As recent clinical investigation with FMS-like tyrosine-3 inhibitors demonstrated, targeting IK with selective inhibitors can have a modest clinical benefit.