The test demonstrated statistical significance for the indirect effect of level of integration on negative stress (p = 0.019), positive stress (p = 0.021), and satisfaction (p = 0.020), taking into account the mediation effect of threat.
The outcome of fixed-effects model analysis demonstrated statistical heterogeneity, so we selected the random-effects model (Dersimonian and Laird method).
Canagliflozin 300 mg demonstrated statistical superiority to sitagliptin in HbA1c-lowering effect (upper limit of the 95% CI less than 0.0%).
For example, previous publication studying the effects of HLA mismatch has already demonstrated the statistical effect (bias towards null) with misclassification involving only 2 3 patients among 130 individuals (Leung et al, 2001).
With relatively few patients, the subgroup analyses fail to demonstrate statistical significance, despite effect sizes and trends very similar to that seen in this overall analysis.
The use of an unresponsive instrument will result in a failure to demonstrate statistical and clinical significance regardless of the true treatment effect [ 12, 23].
Although single clinical trials can demonstrate statistical superiority of analgesic over placebo, random variation means that, if small, they provide a poor estimate of effect size [ 10].
It was inferred that smaller studies with larger effect sizes were more likely to be published, and thus they had a higher probability of demonstrating statistical significance.
The results did not demonstrate statistical heterogeneity.
When our GLM demonstrated a significant overall statistical effect and a significant treatment group effect, we further explored pairwise comparisons between the exercise training groups vs. the control group using a Dunnett-Hsu post-hoc assessment.
The occurrence of cerebral metastases may confer a worse prognosis, but very few patients had these at the time of metastatic diagnosis and therefore no statistical effect could be demonstrated.
