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Eight aptamers demonstrated specificity for the neurotensin receptor.
This primer pair demonstrated specificity for at least six groups of plant trypanosomatids and did not amplify from insect trypanosomatids.
New primers were designed to target the 16S rRNA gene, as a universal maker for fish detection, with fully demonstrated specificity for a wide range of fish species.
While these inhibitors were indeed potent against HDAC8, and even demonstrated specificity for HDAC8 over HDACs 1 and 6, there were no structural data to confirm the mode of binding.
The most potent in a series of synthetic inhibitors based on 5- 5,6-dichloro-2-indolyl -2-methoxy-2,4-pentadienamide (INDOL0) has demonstrated specificity for the osteoclast enzyme, over other V-ATPases.
For example, seco-CI-InBf (5a) and seco-CI-TMI (5c) demonstrated specificity for AT-rich sequences, particularly by reacting with the underlined adenine-N3 position of 5′-AAAAA 865 -3′.
Similar(51)
These biomechanical effects were not observed in response to S-nitroso-D-cysteine, demonstrating specificity for the naturally occurring isomer.
4HT alone had no sustained effect on the pattern of allelic expression in parental G401 cells, demonstrating specificity for the SMARCB1 effect.
Knockdown of other phosphatases PP5 or PP1γ1 and subunits PP6R3 or ARS-A did not reduce IR activation of DNA-PK, demonstrating specificity for PP6R1.
Furthermore, agnathan fish possess an adaptive immune system based entirely on clonal rearrangement of LRRs rather than immunoglobulins and the resulting LRR domains demonstrate specificity for individual strains of bacteria [33] [36].
(A – J ) Low-magnification sense controls (A, D, G ) demonstrate specificity for each probe.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com