Sentence examples for demonstrated side effects from inspiring English sources

Various medications including proton pump inhibitors and H2 receptor antagonist are available for the treatment of gastric ulcers, however clinical assessment of these medications have demonstrated side effects, incidence of relapses and drug interactions [4] thus, there is need to identify more effective and safe anti-ulcer agent.

Prednisolone thus demonstrated side effects to bone not observed with VBP15 treatment.

Patients treated with abiraterone acetate have demonstrated side effects related to mineralocorticoid excess due to the drug's mechanism of action, such as fluid retention, hypertension, and hypokalemia.

There have been no demonstrated side effects of sPLA2 IIa inhibition in animal models of disease and the phase II clinical trial of an sPLA2I in humans provided evidence of some liver toxicity only at the highest doses (1,000 mg/day) [ 17].

More importantly, artemisinins demonstrated minor side effects to normal cells and manifested the ability to overcome multidrug-resistance which is widely observed in cancer patients.

Transitioning patients who were intolerant of latanoprost 0.005 % to BAK-free travoprost 0.004 % reduced IOP, improved hyperemia levels, and demonstrated few side effects.

Research studies have demonstrated no side effects of recommended creatine use on kidney, liver and/or the heart.

While HCS using cell-based assays facilitate the rejection of compounds that are directly cytotoxic, they are unable to identify those that lack the desired therapeutic effect in vivo, or demonstrate deleterious side effects on complex developmental or physiological processes, such as cellular migration or synaptic transmission, respectively.

Antidepressants in general, however, demonstrate serious side effects such as anxiety disorders, gastrointestinal problems, and sexual dysfunction in patients; therefore, it is important to find an effective way to prevent the occurrence of depression.

The initial randomized, double-blind, placebo control study of high-dose ibuprofen in CF did not demonstrate serious side effects during 4 years of therapy with ibuprofen sufficient to achieve peak plasma concentrations of 50 100 mcg/L [ 8].

Initial studies showed TDF to be a safe drug in HIV-infected patients, with a post-marketing survey of 10 343 patients demonstrating renal side effects in only 0.5% of patients [ 4].