Sentence examples for demonstrated roles of from inspiring English sources

Aside the expected and demonstrated roles of these filaments in intracellular transport processes and cellular movements, especially in the context of cell division, the septin filaments have been predicted to serve also as scaffolds for the docking of other regulatory or signaling proteins [10].

A requirement for autophagy in the epidermis is consistent with previously demonstrated roles of autophagy in cellular remodeling [ 17, 18].

Some epidemiological studies have demonstrated roles of cagA positive H. pylori in the development of atrophic gastritis, peptic-ulcer disease and gastric carcinoma [ 61, 62].

The presence of these rootlets and rootlet-like structures is consistent with the demonstrated roles of both IL1 and IL2 neurons in transducing mechanosensory stimuli (Hart et al., 1999; Goodman, 2006; Lee et al., 2012).

Genes downregulated in spt were chosen because of the demonstrated roles of T-box genes as transcriptional activators [ 45, 46]; fold-changes for differential expression between spt and wild-type ranged from -1.68 to -16.67 among the 48 genes.

FoxM1 is a transcription factor key to malignant progression of various tumors with the demonstrated roles of FoxM1 in stemness, chemoresistance, invasivness, EMT, and the maintenance of self-renewal capacity of certain types of SCs.

On the other hand, because of the demonstrated role of carboxylesterases in (pro drug metabolism, the risk of undesirable drug-drug interaction should also be considered.

This is justified by the demonstrated role of the microtubules in the force generation.

These results are consistent with the previously demonstrated role of ATF3 on ER stress induced apoptosis in islets [14], [25].

These studies have clearly demonstrated role of formulation in retaining activity of biologics.

This, however, is at odds with the demonstrated role of SASP in stimulating the proliferation of transformed cells.