Sentence examples for demonstrated roles from inspiring English sources

Despite demonstrated roles in experimental animals, the exact function of these and other ultratrace elements (e.g., tin, lithium, aluminum) in human tissues and indeed their importance for human health are uncertain.

DUSP4 specifically targets JNK, and both DUSP1 and 10 have demonstrated roles in inflammation.

Interestingly, we found that zebrafish Her8a is essential for the inhibition of neurogenesis, the converse of the earlier demonstrated roles for Hes6 homologues.

However, multiple lines of evidence have demonstrated roles for β-catenin signaling in alveologenesis but not in ductal side-branching [48].

While previous studies have demonstrated roles for neural activity in circadian output [59], [60], in sustaining molecular rhythms [34], and in synchrony [21], [35], [56], [61], our work strongly suggests a substantial role in circadian timing.

While we could not find studies demonstrating a direct regulation of integrins by PKA in DC, several studies have demonstrated roles for regulation of β2 integrins by PKA in neutrophils.

Given the previously demonstrated role of these neurons in conceptual representations13,14, are they causally involved in the perceptual alternations observed in BR?

On the other hand, because of the demonstrated role of carboxylesterases in (pro drug metabolism, the risk of undesirable drug-drug interaction should also be considered.

This is justified by the demonstrated role of the microtubules in the force generation.

Beyond its demonstrated role in herpesviruses, Arg is also common in a tornovirus recently found in Florida turtles with FP [63].

These results are consistent with the previously demonstrated role of ATF3 on ER stress induced apoptosis in islets [14], [25].