Sentence examples for demonstrated requirement from inspiring English sources
One study [17] initially demonstrated requirement of the CD36 C-terminus for endocytosis and nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) activation, whereas other reports showed that internalization of LTA is not necessary for signal transduction [19], [20].
In the stn8 mutant phosphorylation of CP43 at all time points was lower than in the wild type or stn7 plants (Figure 6A,B), while no any significant phosphorylation was detected in stn7stn8, which demonstrated requirement of both STN7 and STN8 for quantitative phosphorylation of the thylakoid proteins [7], [17].
Using deletion constructs, Ostermeyer et al. [ 26] demonstrated requirement of a hydrophobic domain for lipid droplet targeting of caveolin-1.
It is important to note that none of these ideas is inconsistent with the demonstrated requirement for α'/β' activity during the post-training consolidation period.
Gene deletion experiments in mouse have clearly demonstrated requirement for Tbx5 and Tbx4 to establish the Fgf10-Fgf8 positive feedback loop between the limb mesenchyme and overlying ectoderm.
Thus, reduced hippo signaling and pS127-YAP levels appear effectively uncoupled from automatic nuclear localization, in keeping with the recently demonstrated requirement for tyrosine phosphorylation to mediate the transition [ 29].
Examination of the design space for an optimal adhesive demonstrated requirements for strong adhesion and low stiffness to maximize the strength of the adhesive-coated suture repair construct.
Our results demonstrate requirements of extracellular calcium and TRPC channels in BDNF responses, a perspective also supported by other recent studies [44], [45].
Together, these observed phenotypes demonstrate essential requirements for stable H+ efflux in normal craniofacial development, osmotic balance, and tail regeneration.
