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The level of mRNAs encoding proteins present in cells differentiating along ectodermal (E-Cadherin), mesodermal (Brachyury, Mixl1), and endodermal (Sox17, Fox2a and CXCR4) pathways demonstrated no substantial difference in CTX-treated compared to control EBs between 12 and 20 days (Figure S1).
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In conclusion, the results of this study demonstrate no substantial differences in anti-depressive effectiveness between olanzapine, quetiapine, risperidone and ziprasidone in a clinically relevant sample of psychotic patients with moderate depressive symptoms.
Additional support for this view is provided in this analysis demonstrating no substantial differences between the outcome subgroups in the proportion of the non-resected perifocal F-FDG hypometabolism and decreased C-FMZ binding in both VOIs (Tables 4 and 5), which also had a weak predictive value for individual freedom from seizures (Tables 6 and 7).
The clinical burden of severe renal flares is substantial however, previous studies have demonstrated no significant difference in HRQoL between patients with and without renal involvement [ 9].
The scoring system also demonstrated no substantial ceiling or floor effects.
No substantial difference was demonstrated regarding the other optic characteristics between the two.
We merely report the results of the first model to demonstrate there are no substantial differences between the results of an analysis of the whole range of Microcystis concentrations versus a subset including only the highest concentrations.
Fremerey et al. [15] reported no substantial difference between the interventions, with two patients demonstrating a loss of abduction and external rotation following operative management compared to one patient following non-operative rehabilitation (P > 0.05).
There was no substantial difference of pain-relief between the PCEA and PCIA or at least that the demonstrated difference of pain relieve associated with two analgesic methods was so small that it could not be clinically relevant.
No substantial difference was observed.
No substantial difference was observed with age.
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