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Of concern, some emergency medications, including lorazepam [ 4, 7], have demonstrated instability at real-world ambulance temperatures.
Drugs with demonstrated instability when stored outside of manufacturers' recommendations included two cephalosporin antimicrobial drugs, epinephrine, and oxytocin.
Tumors were classified as MSI-H if > 30% of markers demonstrated instability and as MSS/MSI-L if < 30% demonstrated MSI [ 22, 23].
Tumours were classified as MSI-high if 30% or more of the repeats were unstable and MS-stable/MSI-Low if less than 30% of the repeats demonstrated instability (Phipps et al, 2011).
Tumourclassification was as follows: MSI-high if three or more markers demonstrated instability, MSI-low if one or two markers demonstrated MSI, and MSI-stable if no marker exhibited MSI.
It is notable that both strains also demonstrated instability in their sporulation phenotype; in some runs, the ATCC strain failed to sporulate at all and the number of heat-resistant spores in the UK-14 strain reached only 10 CFUs/mL.
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Indeed, MD simulations of a homology model based on early crystal structures demonstrated instabilities that helped point out problems with these structures.
However, all SAW simulations demonstrate instability in the complex after sympatric zones are established between terminal populations.
Degenerative spondylolisthesis is divided into dynamic spondylolisthesis, which demonstrates instability on flexion/extension radiographs, and the static subtype, which does not show radiological evidence of instability [48].
The other tumour, from an Amsterdam criteria positive kindred, did not demonstrate instability by any technique.
This is consistent with previous theoretical work demonstrating instability of much simpler attractor networks based exclusively on structured excitation.
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