This was further initially demonstrated for Map1p, for which we observed subtle coordinated down-regulation of target mRNAs upon MAP1 overexpression, indicating that Map1p preferentially negatively affects gene expression of target messages.
Sequential ET and then PT has been demonstrated for BLUF initially in the dark state and concerted PCET for BLUF initially in the light state.
Recently, structures for lossless ion manipulations (SLIM) have been developed and initially demonstrated for a range of ion manipulations, including ion mobility separations, ion trapping, and switching of ions between different paths.
This was initially demonstrated for influenza viruses by a simple membrane fusion assay, hemolysis of erythrocytes that occurs only if virus particles containing cleaved HA or HEF are exposed to acidic pH (Formanowski et al., 1990; Huang et al., 1981; Kitame et al., 1982; Lenard and Miller, 1981; Maeda and Ohnishi, 1980; Ohuchi et al., 1982).
The ability of gut microbiota to affect levels of hepatic enzymes was initially demonstrated for carbohydrate-metabolizing enzymes.
Benefits from video game-based therapy were initially demonstrated for upper-limb recovery [ 9], but, at present, the results on balance and mobility are inconclusive [ 1, 10].
This finding, initially demonstrated for the promoters of heat-shock proteins (HSPs) and MDR1 genes, was subsequently extended to several other promoters and appears to be cell dependent (Jin et al, 2000; Minuzzo et al, 2000; Feuerhahn et al, 2011).
The occurrence of the A/D transition was initially demonstrated for bovine complex I in preparations of heart submitochondrial particles (SMP) [11] and enzyme isolated by the Hatefi protocol [12].
1 Such disease progression/clinical outcome (DPCO) models may provide reasonable predictions of clinical outcome based on the observed dynamics of disease progression biomarkers, as was initially demonstrated for colorectal cancer 13 and non-small cell lung cancer.
