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But as Don Aldridge has demonstrated in "The Rescue of Captain Scott" (1999), this is so far from the truth as to constitute a flat-out lie.
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Moreover, we have recently demonstrated that the rescue of ADAR2 activity in astrocytoma cells prevents tumor growth in vivo, through the modulation of a specific molecular pathway involved in the cell cycle G1/S checkpoint [ 22].
Ex vivo osteoclastogenesis assay further demonstrated the rescue of osteopenia/hyper-osteoclastogenesis in Sf via M-CSF neutralization.
We use clones from a genomic fosmid library of Drosophila pseudoobscura to demonstrate the rescue of RNAi phenotypes in Drosophila melanogaster muscles.
Successful rescue from PrPSc was demonstrated in the colony assay as reflected by the absence of proteinase K (PK -resistant PK -resistant8# cells after PrPScreatment.
A few recent studies demonstrate that modulating proteostasis could help in the rescue of the misfolded ΔF508-CFTR protein [18] thus highlighting the therapeutic potential of proteostasis augmentation in cystic fibrosis lung disease [19, 20].
LaVail and colleagues [3] first demonstrated in the RCS (the Royal College of Surgeon) rats that a single injection of FGF-2 successfully rescues photoreceptors from degeneration [3].
Macroautophagy (refered as autophagy) has first been demonstrated to be a self-proteolysis system involved in the rescue of the cell to maintain homeostasis.
Cell death was also assessed by DAPI staining and Western blotting which turned out to be consistent in demonstrating the rescue effect of HGF in saving Huh7 cells from sorafenib-induced cell death and 3(c)).
These data clearly demonstrate that cytoB prevents the rescue of cell death observed in cocultures and suggest that TNTs may be involved in the rescue process.
Histological analysis qualitatively demonstrated the partial rescue of myotube atrophy conferred by inhibitor treatment.
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