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The feasibility of using strain gages was then demonstrated in model experiments in which values of the dynamic complex stress intensity factor (CSIF), Kd, were obtained.
It has been also demonstrated in model simulations that dual oscillations (i.e. subset of cells fire synchronously during a given gamma cycle) mediate the active maintenance of multiple short-term memories.
It has been demonstrated, in model neurons, in slice preparations, and in whole brains, that neural synchronization is facilitated by the addition of optimal amounts of random fluctuations, or "noise," to a neural network, whereas less than optimal amounts have less effect and larger than optimal amounts destroy synchronization [3].
Hence, removal of senescent cells is beneficial and has been demonstrated in model animals [ 84].
As demonstrated in model eukaryotes, nucleosome positioning can be a major factor in regulating gene expression.
There is unresolved controversy about whether direct carcinogenic effects of some oestrogen metabolites, which can clearly be demonstrated in model systems, also have a significant impact in women.
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It has been demonstrated in models that coevolutionary clines may result from multiple effects [68].
In vivo, the suppressive activity of adoptively transferred MDSCs could be demonstrated in models of inflammation [49] and cancer [50].
The cost-effectiveness of nab-paclitaxel in MBC has also been demonstrated in model-based and retrospective analyses [ 22, 23].
These results support the findings demonstrated in models of pulmonary fibrosis due to irradiation.
These findings confirm the proliferative role of progesterone demonstrated in models of normal human breast [ 9] and in the murine mammary gland [ 10].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com