Decreased numbers of mature DCs have been demonstrated in the circulation, tumor bed, and draining lymph nodes, in multiple tumor models.
Although most studies have focused on systemic maternal complement activation, complement activation products have also been demonstrated in fetal circulation, decidua, chorionic villi, and placental vascular walls in women with preeclampsia, supporting local complement activation with placenta targeting as a mechanism of interest for preeclamptic placental pathology [ 9].
Myogenic constriction is an important mechanism of blood flow regulation; however, it has never been demonstrated in the human coronary circulation.
Indeed, this prognostic role has been demonstrated in peripheral and central circulation, in microcirculation and large arteries, and independently from the used endothelial stimulus (3, 29, 39).
A correlation between the open-angle glaucoma and existence of impaired blood flow in retinal and extrabulbar circulation was demonstrated in clinical trials [ 10].
It is noteworthy that some regions, where WNV circulation was demonstrated in animal and vectors, did not reported any human case.
Sequestration of PRL from the circulation was demonstrated in vivo by tracing radiolabelled PRL from blood to milk and in vitro by following the transit of intact PRL through breast epithelial cells [ 11].
Thermohaline Circulation: Thermohaline circulation of the ocean is demonstrated in a rendition of the classic Stommel-Arons experiment.
In Namibia, although virus circulation has been demonstrated in humans (9 – 11 ), little information is available on the distribution and the molecular characterization of RVFV circulating there.
By 2002, serosurveys demonstrated WNV circulation in >6 eastern Mexican states and along its northern border with the United States (3 – 5 ).
