Your English writing platform
Discover LudwigExact(37)
As double stranded, single stranded siRNA (ss-siRNA) has demonstrated gene silencing activity but still requires efficient carriers to reach its cytoplasmic target.
Intravenous administration of the optimized polyplexes in mice led to gene expression in the brain, which upon further immunohistochemical analysis demonstrated gene expression in neurons.
The approach hadn't seemed within close reach until geneticists last year demonstrated gene drive in fruit flies and yeast by harnessing a gene-editing technique called CRISPR/Cas9.
Additionally, previous work has demonstrated gene exchange among Neisseria species [8], [35], [36], [37].
We further demonstrated gene expression of HNF6-regulated genes, namely, HSP105B, CYP51, and C/EBPα to be significantly upregulated upon siRNA-mediated functional knockdown of FOXA2.
Recently, we demonstrated gene amplification of adjacent genes encoding platelet-derived growth factor receptor alpha (PDGFRα) and c-Kit in a subset (19%) of MPNST [2].
Similar(23)
Recent studies using the Aire knockout mouse have demonstrated gene-dose dependency and disease modifier loci, returning the onus of exploration to human genetics.
Subsequent studies demonstrated genes encoding the expression of regulatory proteins and toxins during intracellular growth of the pathogens [37].
Several other intervention studies also demonstrated gene-diet interaction on obesity (Table 1).
Overall, within the first 5 months of transplantation, both patients in the Frankfurt trial demonstrated gene-marking in approximately 15% of circulating neutrophils with significant levels of ROS activity.
Curing of this "rescue" plasmid from the bacterial population resulted in a cessation of growth, demonstrating gene essentiality.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com