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Immunohistochemical staining demonstrated entry of P. gingivalis into different periodontal cells.
Finally, several in vitro and in vivo studies have demonstrated entry, recruitment, and spread of misfolded α-syn and tau seeds to neighboring cells and/or anatomically connected brain regions (Costanzo and Zurzolo, 2013; Guo and Lee, 2014).
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The potential of the reaction to streamline synthetic routes by sequential reductive processes has also been demonstrated (entries 12 and 13).
Of note, in a study of individuals with type 2 diabetes undergoing vitrectomy following intravitreal injection of bevacizumab, mean plasma VEGF concentrations were reduced approximately 10-fold (from 92.0 to 9.7 pg/ml) 1 day after injection, clearly demonstrating entry into the systemic circulation [ 28].
Video laryngoscopy has demonstrated shorter entry to POGO (percentage of glottic opening) and entry to tube times, improved glottic view, and lower incidence of esophageal ETT placement [ 19– 22].
We demonstrated that entry was inhibited by a MAb to L1 and was dependent on the presence of A28, two of the proteins known to be essential for VACV entry in mammalian cells.
The authors analysed mycobacterial gene expression at regular intervals during oxygen deprivation and demonstrated that entry of M.tb.
We have demonstrated the entry and persistence of 3 phylogenetically distinct lineages of SAFV-2 in Denmark.
In these experiments, the presence of antibodies that neutralized most human isolates of SARS-CoV demonstrated enhanced entry into renal epithelial cells (10).
The benefit of ALP to improve clinical care in a cost-effective way needs to be demonstrated before entry into clinical practice; whilst some support has been given for quantifying LDL-p in the US [15,45], in most European health care systems this is not the case and we would support waiting for clearer evidence that cost benefit is obtained.
So far, few missions have demonstrated re-entry from interplanetary space, which requires a considerably greater velocity change than the more common Earth orbit re-entry missions, and so far none have dealt with the planetary protection issues.
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