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Moreover, "IPA-Core-Analysis" revealed that this small subset of tightly inter-regulated molecular targets showed influential participation in many canonical signaling pathways and demonstrated defined roles in multifarious biological functions.
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However, the complex situation, with protein bound circulating IGF-I and locally produced IGF-I, makes it difficult to demonstrate defined roles for the various IGF-I compartments, particularly when binding proteins themselves may have independent regulatory functions across muscle membranes [ 11, 12].
Draw up ground rules and clearly defined roles for yourselves.
However, no defined role for GA in seed development has been demonstrated in any species.
He doesn't have a defined role.
I definitely would like a more defined role.
"Everybody has to have a clearly defined role," Prince added.
micROS allows different ways for defining roles.
This work now demonstrates a defined functional role of this domain.
-Women's FGD participant 5, early 20's, unemployed These women's comments indicate a deep connection between cultural identity and defined gender roles, and demonstrate a sense of threat from and animosity towards disruptive ideas imposed by outsiders, harkening back to colonialism: "My parents always reminded me of how important preserving our culture is.
To provide a mechanistic insight into the demonstrated essential role of macromitophagy in defining longevity of chronologically aging yeast under CR conditions, we used electron microscopy (EM) to compare the age-related dynamics of changes in the size, number and morphology of mitochondria in WT cells to that in macromitophagy-deficient atg32Δ cells.
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