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Only one of the 89 miRNAs, miR-218, demonstrated concordant changes in copy number and expression.
Split-sample validation by randomization, age, entry time or residence of patients demonstrated concordant findings.
Retrospective testing of some targets using genomic templates demonstrated concordant results to those observed using synthetic templates.
As expected, many proteins identified in S. Typhi demonstrated concordant differential expression with a homologous protein in S. Typhimurium.
Two miRNAs, miR-218 and miR-216, were common to training and all test sets, however, only miR-218 demonstrated concordant loss of copy number and expression (Figure 1).
Quantitative RT-PCR and immunohistochemical studies demonstrated concordant results.
Similar(43)
IRS-PCR demonstrates concordant results with PFGE analysis in studying the genetic relationships among K. pneumoniae isolates, and serves as an excellent epidemiological tool for this bacterium.
Patients with multiple CRCs due to HNPCC are expected to demonstrate concordant MSI-H and loss of expression of the same mismatch repair gene in all cancers.
Status epilepticus models classically demonstrate concordant human histological changes of severe neuronal loss, granule cell dispersion, remodeling of mossy fiber structures and neurogenesis.
It may be feasible to gain acceptance of a surrogate AD biomarker with a small number of trials demonstrating concordant treatment effects on the biomarkers and clinical symptoms.
This choice was made because increased expression of type I interferon-inducible mRNAs is a direct molecular consequence of increased expression of IFNα proteins, and because type I interferon-induced mRNAs are easy to measure by either RT-PCR or microarray-based technologies and demonstrate concordant overexpression in blood and involved tissue in SLE [ 38].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com