Sentence examples for demonstrated by substantial from inspiring English sources
The efficacy of psychological treatments emphasising a self-management approach to chronic pain has been demonstrated by substantial empirical research.
In addition, long-term adalimumab treatment was associated with improved HRQoL as demonstrated by substantial and sustained improvements assessed using a disease-specific measure (ASQoL).
MiR-210 also induced pulmonary vascular remodeling, as demonstrated by substantial muscularization and medial thickening in the distal pulmonary vessels (Fig 4G and H).
Abdul-Ghani et al. (22) investigated the prognostic performance of insulin secretion/insulin resistance indexes using ROC analysis to determine their predictive accuracy for progression to type 2 diabetes and reported that insulin secretion/insulin resistance is the best predictor of type 2 diabetes demonstrated by substantial sensitivity and specificity.
l-Methionine and l-methionine ethyl ester (MEE) are each excellent substrates for C. jejuni MetK, and each supported significant DNA methylation, as demonstrated by the substantial protection from cleavage by the restriction endonuclease HpaII, with a very low abundance of bands below 500 bp; the great majority of DNA is found as the full-length, completely methylated linear substrate (2.69 kb).
This is demonstrated by our substantial growth in R&D investment between 2003 and 2007," Koestler says.
This caused activation of the RAS demonstrated by a substantial rise in plasma aldosterone (Fig 5A) and plasma corticosterone (Fig 5B) in both mouse genotypes.
