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Moreover, trafficking towards other subcellular compartments occurs normally as well, as demonstrated by normal ribeye (69) localization to the synapse in cc2d2a−/− photoreceptors (Fig. 5G and H).
OECs normal cell function was unaffected by genetic modification as demonstrated by normal microscopic morphology and the presence of the low affinity neurotrophin receptor (p75NGF) following viral transduction.
The specificity of decreased Gdnf expression in Ptc1−/−UB kidneys is demonstrated by normal expression of Osr1, Six2, and CITED1, each of which marks mesenchymal precursor cells [22], [23], [24], [25], [26]; Wnt4, a marker of pretubular aggregates [27]; and Wnt9b which is required for the earliest inductive response in metanephric mesenchyme and acts upstream of Wnt4 [28] (Figure S6).
They found that propolis did not induce kidney damage in rats as demonstrated by normal levels of urea and creatinine.
Furthermore, MMP14 did not impair osteoblast activity as demonstrated by normal mineralization of extracellular matrix nodules (Fig. 3C).
The resolution of inflammatory response, demonstrated by normal IL-10 mRNA-induction, also seems to be unaffected by osteopontin-deficiency, thus allowing the timely onset of myocardial remodeling.
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This preliminary analysis showed that SUVmax, SUVmean35, and SUVglu had certain linearity and a data distribution close to a normal distribution as demonstrated by normality tests (Shapiro-Milk and Kolmogorov-Smirnov) and QQ-plots.
Nevertheless, mammary epithelial differentiation is normal in lactating Akt1-/ mice, as demonstrated by physiologically normal levels of Stat5 activation, normal upregulation of the terminal differentiation marker Npt2b, normal downregulation of the virgin-specific transporter NKCC1, normal expression of all major milk proteins, and normal intraepithelial lactose levels.
At 72 hpf, duct development appeared normal in morphant embryos, as demonstrated by a normal pattern of GFP-labeled duct cells in Tg -3.5nkx2.2a GFP ia3 Tg -3.5nkx2.2a GFP ia3 Additransgenics 7D-G].
This paper identifies the source of this problem in the interplay of the global pressure-update formula with the numerical boundary conditions and presents an improved projection algorithm which is fully second-order accurate, as demonstrated by a normal mode analysis and numerical experiments.
This disorder shows clinical features practically indistinguishable from acute myocardial infarction in the absence of significant coronary artery stenosis (which can be demonstrated by a normal CT coronarography) with systolic dysfunction that is completely reversible within a few days or weeks [24, 28].
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