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Our laboratory's earlier studies, [ 20, 21] the Praskos' study, [ 22] and the work of Neumeister et al., [ 23] Loving, [ 24] and Bloching [ 25] all indicated that Late Wake Treatment (LWT), when combined with bright light, produces remarkable antidepressant responses, demonstrated by dramatic contrasts between bright light and placebo.
Our early studies [ 35, 36] the Praskos' study [ 37], and especially the work of Neumeister et al. [ 38], Loving [ 39], and Bloching [ 40] suggested that partial sleep deprivation combined with bright light produces remarkable antidepressant responses, as demonstrated by dramatic contrasts between bright light and placebo.
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The fundamental role of UHRF in the maintenance of DNA methylation is demonstrated by the dramatic reduction in global CpG methylation in homozygous Uhrf-null ES cells and embryos.
Serious impacts of pharmaceuticals in the environment are also demonstrated by the dramatic decline of three vulture species in India and Pakistan.
Activation of the renin-angiotensin-aldosterone axis is central to the pathogenesis of scleroderma renal crisis, as demonstrated by the dramatic improvement in survival since ACE inhibitors have been used to treat the condition.
The effectiveness of cervical cancer screening has been demonstrated by the dramatic decline of cervical cancer in developed countries in which programs relying on repeated cervical Pap smears have been successfully implemented [ 2, 3].
When miRNA-200c levels were restored in any of these cells, they lost the ability to proliferate in vitro, as demonstrated by a dramatic decline in clonogenicity, and they lost the ability to proliferate in vivo, as demonstrated by an inability to generate tumors or normal outgrowths upon orthotopic implantation in mice.
The occurrence of this force is well demonstrated by the dramatic actin-dependent elongation of the clathrin-coated pit necks in living cells and in cell-free systems (Ferguson et al., 2009; Wu et al., 2010), when the fission reaction is impaired by the lack of dynamin (living cells) or block of its GTPase activity (cell-free system), respectively.
Consistent with previous studies, here we found that Ron∆JM-B possessed higher intrinsic catalytic capability than the wild type receptor, as demonstrated by a dramatic increase in phosphorylation of the activation loop tyrosines and a docking tyrosine, and in expression of an AP-1 reporter in both the presence and the absence of ligand.
However, given the level of awareness of ASF demonstrated by the farmers, the very dramatic clinical signs typically associated with ASF, and the probable absence of the most important differential diagnoses in the study population, this risk is considered low.
As demonstrated by Figure 1C, there was a dramatic decrease in pancreatic luminescent signal soon after the STZ treatment as the β-cell function was lost, and a concomitant spatial shift of the luminescent intensity to the area where liver is located as serum blood glucose levels rose above 300 mg/dl.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com