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For a mediator to be demonstrated, besides an association between the initial and the outcome condition, the possible mediator has to be associated with both conditions.
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In summary, the articles published in this issue demonstrate, besides the marriage of "Methusalem Drugs," the close relationship of the "hormone factory" skin, pharmacotherapy and internal medicine.
Thus far, it has demonstrated little besides a breathtaking determination to think small.
It was demonstrated that besides necrosis and apoptosis, autophagy was apparently associated with PEI-induced cytotoxicity and contributed to aggravated cell damage.
It was demonstrated that besides adequately correlating the load ratio effects, the exponential model also accounts for the slight deviations from linearity shown by the experimental curves.
These results demonstrated that, besides hydroxyl radical and its consecutive products, oxidants produced in SO42− electrolysis at BDD anode played a role in electrochemical disinfection in Na2SO4 electrolyte.
We also demonstrated that besides enhancing chromatography separation and improve product quality, especially for high molecular weight (HMW) aggregate reduction, mixed-mode resins can also help to improve process efficiency in industrial-scale mAb drug manufacturing.
Since the 1960s polysomnographic sleep research has demonstrated that besides disturbances of sleep continuity, depression is associated with altered sleep architecture, i.e., a decrease in slow wave sleep (SWS) production and disturbed rapid eye movement (REM) sleep regulation.
However, recent experimental studies have clearly demonstrated that, besides the efficient handling of the core nanophases, the appropriate treatment of their interfacial region is another major challenge one has to face on the way of target-oriented development of these materials.
The results also demonstrated that besides the reciprocal interaction of epidermal stem cells with dermal cells, the interaction of epidermal stem cells with keratinocytes were critical in epidermis morphogenesis and self-renewal, and application of RA cells could optimize engineering of skin substitutes.
Finally, we calculated exciton fine structure splitting and demonstrated that besides two high symmetry cases, [001] and [111], the bright exciton structure splitting varies strongly with substrate orientation.
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