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This is similar to what has been demonstrated at a single cell level for somatosensory stimuli in the primary somatosensory cortex: stimulus intensity is coded in the primary somatosensory cortex, the conscious percept per se in the prefrontal cortex [23].
An improvement in guideline adherence was demonstrated at a single site following dissemination of the guidelines to all specialists and implementation of a nurse co-ordinator role to ensure that screening/surveillance recommendations matched guideline recommendations [ 4].
MCR has so far only been demonstrated at a single target site in the Drosophila y gene, a locus often used in pioneer studies and which appears to have an unusually high susceptibility for gene targeting (Rong and Golic 2000; Gratz et al. 2013).
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In case of cytotoxic T lymphocytes, it has been demonstrated that at a single cell level a mouse effector lymphocyte can kill one target and has the potential to recycle and kill up to six targets in a sequential manner [3].
Over the past decade, very promising performances have been demonstrated at the single device level or in a collection of a few single units [1 14].
Additionally, mosaicism has been demonstrated at the single cell level.
Bacterial isolate drug sensitivity data were available from 43 patients (50.6%), 3 3.5%) demonstrated at least single drug resistance.
The concept is demonstrated at single cell level using both H adsorption and CO stripping, and the H adsorption (cathodic current) method is extended to stack testing.
In all these models, NST-732 was administered intravenously, animals were sacrificed thereafter, and the selective uptake of NST-732 only by cells undergoing cell death was demonstrated at the single-cell or whole-organ level, by fluorescent detection.
Recently, the critical role for mRNA stability in the induction kinetics of genes encoding inflammatory proteins was demonstrated at single-genes level [ 13].
A. niger PhyA exhibited two pH optima at pH 2.5 and pH 5.0, while A. niger PhyB demonstrated only a single pH optimum at pH 2.5 [ 8].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com