Patients with minor thrombocytopenia (less than grade 3) at cycle 1 may receive an escalated dose of indisulam of 600 mg m−2 at cycle 2, because previous studies have demonstrated a high correlation between the extent of prior chemotherapy and the incidence of haematological toxicity.
Bolhuis and co-workers have demonstrated a high degree of correlation between the extent of imitation of the tutor's song and the level of expression of the immediate early genes ZENK and c-fos in response to stimulation with it [36], [37].
34– 37 Yang et al. demonstrated a high degree of satisfaction with aesthetic results independent of the extent of excision volume by using oncoplastic surgical techniques.
In our study, we could demonstrate that SOCS1 and, at a higher extent, SOCS3, transiently induced by IFN- γ plus TNF- α, could protect keratinocytes from apoptosis by sustaining another RAS-dependent pathway, in particular the PI3K/AKT cascade.
These results demonstrate a much higher extent of microsatellite conservation than previously found in mammals (Moore et al. 1998) but still illustrate an overall dramatic decline of human microsatellite conservation across vertebrates.
Our study demonstrates that LSGs in Arabidopsis thaliana display a higher extent of tissue-specific expression, when compared to non-LSGs.
The result demonstrated that lipid oxidation took place in mince at a higher extent during hydrolysis.
Their assay performances and the analysis of the enzyme activities in solution demonstrate that the supercharged version could be coupled to a higher extent, which resulted in better assay sensitivities.
Treatment of the cells with Bay (2 μM), decreased the TNFα-stimulated expression of mPGES-1 and COX-2, the latter to a higher extent, in 24 h cultures, as demonstrated by flow cytometric analysis.
The number of CFU‐MEGs in BM demonstrated an age‐dependent increase in CFU‐MEGs for both groups, but to a higher extent in ID animals (P = 0.004 by ANOVA, Supporting Information Fig. 2).
