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In Experiment 1, we investigated children's exploratory play after an adult pedagogically demonstrated a function of a toy, after an interrupted pedagogical demonstration, after a naïve adult demonstrated the function, and at baseline.
Most notably, in vitro results of phalloidan staining and cell motility assays demonstrated a function for ICAM-2 independent of its known immune stimulatory effect.
We tested the efficacy of the Wnt3a liposomes in an in vivo context, where genetic experiments have demonstrated a function for β-catenin dependent Wnt signaling in hair follicle neogenesis [24].
In vitro studies of the past decade have demonstrated a function of ZO-1 in organisation of confluent cell layers.
Small interfering (siRNA) knockdown and viral overexpression studies of hepatic Sort1 in humanized mice with different genetic backgrounds demonstrated a function for Sort1 in altering LDL-C and very-low-density lipoprotein (VLDL) levels by modulating hepatic VLDL secretion.
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These results demonstrate a function of USP13 in ERAD downstream of retrotranslocation and suggest a potential functional interplay between USP13 and Bag6 that is required to maintain retrotranslocated substrates in a soluble and degradable state.
Au-Yeung, B.B. et al. A genetically selective inhibitor demonstrates a function for the kinase Zap70 in regulatory T cells independent of its catalytic activity.
When the expression of HSF2 was restored, the biological effect was reversed (Figure 4), thereby demonstrating a function of HSF2 on invasiveness.
Of these 119 genes, most of them demonstrate a function related to metabolism, especially amino acid transport and metabolism (Fig. 1).
Here, we demonstrate a function for the Drosophila lipoprotein LTP in conveying information about dietary lipid composition to the brain to regulate Insulin signaling.
These data demonstrate a function for BAF180 in promoting genome stability that is distinct from its well-characterized role in transcriptional regulation, uncovering a potent mechanism for its tumor-suppressor activity.
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