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Further, compounds with c log P's ⩽ 3 demonstrated a dramatic reduction in CYP3A4 inhibitory activity.
A patient with a KIT L576P vaginal mucosal melanoma and extensive metastases to lymph nodes demonstrated a dramatic reduction in metabolic activity with Sprycel [37].
Immunohistochemical analysis of these lesions demonstrated a dramatic reduction in the levels of HIF as well as VEGF in the Digoxin-treated animals compared to control mice (Fig. 6).
Majority of techniques have demonstrated a dramatic reduction in capture efficiency when the whole blood sample is employed.
Lung tissue histopathology demonstrated a dramatic reduction in neutrophil infiltration and caspase-stained cells in the multi-trauma + EP group.
Immunohistochemistry also demonstrated a dramatic reduction in both ubiquitin- and LC3-positive dystrophies, surrounding the Abeta plaques.
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The three-dimensional FEM simulation demonstrates a dramatic reduction effect that is difficult to achieve by conventional measures.
(c) Same experiment in the presence of free heparin (50 μg/ml) demonstrating a dramatic reduction of adhesion frequency due to the blocking of the HBHA adhesion sites.
Recent studies demonstrate a dramatic reduction in mortality following variceal bleeding of 20% 6-week mortality 55 and 15% in-hospital mortality, 5 with contributions from improved endoscopic, pharmacological and radiological therapies, notably TIPSS.
When postintervention evaluation demonstrated a dramatic year-over-year reduction in volatile agent acquisition costs, we undertook a retrospective analysis of volatile anesthetic purchasing data using time series analysis to determine the impact of our educational initiative.
Specifically, we demonstrate a dramatic stepwise reduction in CNFD, CNFL, and CNBD with an increase in TC using the latest third-generation IVCCM in diabetic patients with increasing severity of neuropathy compared with control subjects.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com