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In earlier studies, Laws et al. (Toxicol. Sci., 58, 366 376, 2000) demonstrated a delay in female rat sexual maturation induced by ATR, effects that could equally have been caused by inhibition of hypothalamic GnRH release.
Comparative pathogenesis studies demonstrated a delay in RB-C22v spread to, and decreased replication in the tonsils, a 102 to 107 log10 reduction in virus titers in lymphoid tissues and blood, and an overall delay in generalization of infection relative to BICv.
Animals receiving vaccines with the PkCSP and or PkSSP2 antigens demonstrated a delay in appearance of parasites in the blood, consistent with killing of sporozoites or infected liver cells and development of fewer liver schizonts [60].
Animals treated with anti-CCL20 antibodies demonstrated a delay in tumor appearance – in the control group on day 28, 100% of animals developed visible tumors, while in the anti-CCL20-treated group, only 60% appeared with tumors on the same day.
Cerebral MRI was repeated at 24 months of age, which demonstrated a delay of myelination.
Our in vivo xenograft experiments demonstrated a delay in tumor progression when topotecan was combined with bortezomib.
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The first of these three presentations was triggered by severe left upper quadrant pain and subsequent computed tomography (CT) demonstrated a delayed left diaphragmatic hernia containing the splenic flexure of the colon for which he declined treatment.
These data demonstrated a delayed heat shock response compared with the early response observed on the HSP90-p23 complex and AKT phosphorylation.
M20 transgenic mice injected with amyloidogenic or non-amyloidogenic αS demonstrated a delayed and robust induction of brain neuroinflammation that occurs in mice with or without αS pathological inclusions implicating this mechanism in aggregate formation.
Sutherland and Crewther also showed that the initial cortical response of the magnocellular afferents was weaker for low contrast stimuli, and that the magnocellular but not the parvocellular pathway demonstrated a delayed response when stimuli were presented at high contrast, for high compared with low AQ participants.
In Figure 3B, reinfection at 75 days demonstrates a delay in positive growth of free EBs.
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