Practical advantages of low-profile vortex generators, such as their inherent simplicity and low device drag, are demonstrated to be critically important for many applications as well.
Activation of the tryptophan-degrading enzyme indoleamine (2,3 -dioxygenase was demonstrated to be critically involved in tolerance induction to prevent fetal rejection.
Since breast cancer has become the most common tumor among women in the whole world [11], and MTDH has been demonstrated to be critically involved in breast cancer progression and metastasis by our group and others,[4], [12], [13], [14], [15], in this study, we attempted to further investigate the potential role of MTDH in breast cancer development.
Moreover, ER membrane structures and dynamics have been demonstrated to be critically regulated by the presence of various membrane-interacting proteins.
Curiously, the sortilin-related receptor SorLA was recently demonstrated to be critically involved in GFRα and c-Ret sorting and signaling (Glerup et al., 2013).
This is a task in which the hippocampus has been demonstrated to be critically involved in forming a conjunctive representation of the conditioning context during pre-exposure (Barrientos et al., 2002; Rudy et al., 2002; Stote and Fanselow, 2004).
Although BV6-stimulated NF- κB activation was demonstrated to be critically required for Smac mimetic-mediated sensitization of glioblastoma cells towards TMZ, the proapoptotic NF- κB-regulated target genes that mediate this chemosensitization have so far remained elusive.
Now that seeing something and saying something has been demonstrated to be so critically important, it's time that New Yorkers be given the chance to do so below ground in the subways, where we are most vulnerable.
