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The replisome-associated sliding clamp is used as a proof of principle and then the authors go on to show topological loading of the B. subtilis SMC complex onto DNA, and to demonstrate the requirements for ATP binding and hydrolysis on loading; the requirements for the accessory proteins ScpA and B and the requirement for ParB.
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They define the molecular signatures of the phenotype and demonstrate the requirement of TREM2 and APOE for its activation.
A spokesman said: "Incidents like this demonstrate the requirement for the accord to be effective, and for all members to work in collaboration for sustainable change in Bangladesh".
Here, we report that the inhibition of PHGDH expression in various CSLCs severely inhibits their tumorsphere formation capacity, and demonstrate the requirement of PHGDH in maintenance of the characteristic stemness feature of CSLCs.
These findings demonstrate the requirement of GRK3 for odorant-induced desensitization of cAMP responses.
These data demonstrate the requirement of Mfn2 expression for PGC-1β-mediated changes in mitochondrial morphology.
We demonstrate the requirement of CD46 CTF processing in immune regulation by two approaches.
More importantly, our results demonstrate the requirement of FLNa for CCL2-induced cell migration.
Taken together, the data demonstrate the requirement for human BLyS for efficient engraftment of human B cells in immunodeficient mice.
These experiments demonstrate the requirement for human BLyS to efficiently reconstitute human B cells in NOD rag1−/−Ppf−/− immunodeficient mice.
Together, these findings demonstrate the requirement of nucleolin for the nuclear transport of the transcription factor Stat1 upon the monocyte differentiation process.
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