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Phosphoproteome analysis and anti-phosphopeptide immunoblotting demonstrate the activation of three major mitogen-activated protein (MAP) kinase cascades in epithelial cells and macrophages by DEPs, crude DEP extracts, and aromatic and polar DEP fractions (Wang et al. 2005; Xiao et al. 2003).
These data demonstrate the activation of AHSV specific T-cell epitopes during vaccination with rMVAs expressing VP2 and NS1.
Taken together, these results demonstrate the activation of caspases and cleavage of tau in the AD brain, events which may precede and lead to the formation of NFTs.
Taken together, these findings directly demonstrate the activation of mesenchymal and MSC markers in cells derived from beta cells, thus supporting the occurrence of EMT in these cells.
In this context, we demonstrate the activation of a common self-renewal and pluripotency-associated gene regulatory network upon cellular reprogramming.
Our results clearly demonstrate the activation of ATM by phosphorylation at Ser-1981 by curcumin treatment.
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Earlier studies also demonstrated the activation of MAPKs in the plants exposed to salinity (Munnik et al. 1999).
Further, PIM2 triggered phosphorylation of AKT and 4EBP1 (Figure 2C) clearly demonstrating the activation of PI3K pathway.
We demonstrated the activation of caspase 3 in Myc down-regulated cells also using the siRNA methodology.
Combining wild type and mutant profiles of these transcripts demonstrates the activation of a complex genetic program that delineates symbiotic nitrogen fixation.
Several studies have demonstrated the activation of the Akt/mTOR pathway in various sarcomas [ 7– 9].
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