Sentence examples for demonstrate that the targeted from inspiring English sources

In particular, the recent development of strategies to conditionally induce the or knockout the function of genes in a tissue specific manner has enabled investigators to engineer mice to demonstrate that the targeted inactivation of specific oncogenes can be effective in inducing sustained regression of tumors.

This variation can be particularly useful for ecological studies: the accumulation of transcripts of the targeted gene can be quantified in several independently transformed lines, not only to demonstrate that the targeted gene was in fact silenced but also to examine the quantitative relationship between gene expression and phenotype.

The ex vivo studies with PPB-PEG-IFNγ therefore demonstrate that the targeted construct is pharmacologically active and was included as proof of concept.

Overall, our data demonstrate that the targeting of various viral regions was associated with a similar HIV-1-specific CD8+ T-cell functional profile, whereas "favourable epitope -targeting and HLA-B*5701 repitope -targetingsociandd HLA-B*5701 HLA-B*5701of polyfunctionality.

Overall, these data demonstrate that the targeting of MST4 by miR-4728-3p is a key step for this miRNA to exert its tumor-suppressive effects.

We here demonstrate that the targeting of CypA by a peptide targeting the AIF-binding site on CypA acts as a multitarget neuroprotectant without apparent toxicity effects, and could therefore display advantageous pharmacological profiles.

She said: "The challenge will deliver zero carbon homes and communities and help the housebuilding sector demonstrate that the targets are feasible and can be commercially viable".

These results demonstrate that the target molecule RGD can facilitate the high-efficiency uptake of HRP RGD NPs by PANC-1 cells [28, 29].

ECA calculations are carried out in order to demonstrate that the target criteria can be met using the relevant material data, geometry and load input.

Results demonstrate that the target material exhibits an incredibly broad absorption extended to 813 nm, a small bandgap of 1.53 eV, and a low-lying HOMO energy level of −5.26 eV.

Here, we demonstrate that the target of said factors is IR.