Gnanadhas et al. [56] demonstrated that the potency of AgNPs was based on the type of capping agent used.
In our preliminary effort, we also demonstrated that the potency of catechol compound as Stat3 SH2 inhibitors could be improved by modifying the non-catechol part of the compound structure.
Comparison with ranibizumab demonstrated that the potency of the polyclonal antibody was greater, but not statistically significantly so than that of a panVEGF-A antibody (IC50 = 0.228, 95%% CI 0.17 0.311, p = 0.059).
Several studies have demonstrated that the potency of inhaled nanoparticles can be associated with size-related parameters, including surface area, rather than the more conventional exposure metric of mass concentration [reviewed by Oberdörster et al. (2005)].
One study demonstrated that the potency of C-peptide inhibitors can be substantially enhanced by conjugation to the HIV-1 Tat arginine-rich sequence (referred to as Tat-Ebo).
Although little is known about the transcriptional activity and tissue distribution of GRβ isoforms, Fruchter et al demonstrated that the potency of the dominant negative effect of GRβ on GRα-induced transactivation depends on both the type and the dose of the synthetic glucocorticoids in use [ 16].
This study demonstrates that the potency of PDT vaccine is increased when vaccine cells remain in culture after PDT treatment for an additional time interval (post-incubation protocol) to allow the expression of PDT-induced molecular/biological changes in these cells.
However, the bioassay using the HUVEC scratch assay demonstrated that the potencies of the PRFext and PRFexu were almost identical.
Our studies demonstrate that the increased biological potency of UFPs is related to the content of redox cycling organic chemicals and their ability to damage mitochondria.
These data demonstrate that the anti-inflammatory potency of TZDs is of poor relevance to their insulin-sensitizing properties and suggest that a strong activation of PPAR-γ may expose arthritic patients to drawbacks secondary to excessive adipocyte differentiation.
Landwehr and colleagues [ 24] reported that dipyrone and paracetamol had similar analgesic potencies after retinal surgery, whereas Grundmann and colleagues [ 23] demonstrated that the analgesic potency of dipyrone was superior to paracetamol during the first two postoperative hours after lumbar disc surgery.
