Sentence examples for demonstrate that the pathway from inspiring English sources

The authors find that a pathway involving peroxisome proliferator-activated receptor delta (PPAR-δ) confers organoid-initiating capacity to non-stem cells, and demonstrate that the pathway induces non-stem cells to form tumors in vivo following the loss of the Apc tumour suppressor.

Our results offer insights into the gating charge pathway of KCNQ2 channel and demonstrate that the pathway can serve as a drug target for development of new therapeutics.

There is abundant evidence that hyperactivation of the canonical Wnt signaling pathway promotes tumorigenesis in experimental systems, while observational data demonstrate that the pathway is frequently activated in human breast tumors, especially in basal-like carcinomas, one of the most aggressive forms of the disease [ 1- 3].

Although these observations suggested the operation in mammalian cells of a pathway identical to that in Drosophila, recent studies demonstrate that the pathway upstream of Yap as well as the regulation and functions of Mst1 and 2 are each more diverse and tissue specific than anticipated from genetic analysis of the developing Drosophila eye (see below).

The data also demonstrate that the pathways utilized by stress kinases can be cell and stimulus specific.

Therefore, completion of the human pathway requires either finding new genes or demonstrating that the pathway is fully functional without them.

Comparison of folding for a related substrate from a species with no GroEL/ES demonstrated that the pathway GroEL/ES enforced is correlated to folding in conditions of chaperonin independence.

As mentioned above, the gene expression profile data demonstrate that the RAS pathway is the only pathway deregulated at day 0.

Our results clearly demonstrate that the BMP pathway is essential for the Wnt pathway to inhibit OPC differentiation, as eliminating BMP signalling effectively blocks the effects of Wnt3a.

The results further demonstrate that the major pathway of tyrosine phosphorylation of SLP-76 is independent of LAT and that there is a minor, LAT-independent pathway of tyrosine phosphorylation of PLCgamma2.

The structural equation introduced in this study demonstrated that the pathways to a STEM career are long and complex.