Sentence examples for demonstrate that the establishment from inspiring English sources

To demonstrate that the establishment of E-cadherin and P-cadherin-dependent cell adhesion leads to regulation of gene expression we performed a comprehensive gene expression analysis using large-scale cDNA microarrays.

The results obtained are shown in additional file 11: Table 9, which demonstrate that the establishment of four to six groups for these data was enough to represent the main sources of variability among the selected patterns.

In conclusion, our data demonstrate that the establishment of a dedicated endocrine surgical program at an academic hospital can lead to fundamental shifts in institutional referral patterns, resulting in higher operative volume.

The history of the 2°C target clearly demonstrates that the establishment of an absolute climate target contributes little to effective risk management if major emitters refuse to actually implement corresponding measures because the reduction paths appear too ambitious to them.

Our study demonstrates that the establishment of a comprehensive tumour molecular profile on a metastasis is safe, feasible, and compatible with clinical practice in cancer patients.

Here, we have demonstrated that the establishment of interactions between the diverged regulatory networks in allopolyploids is accompanied by massive homoeolog-specific up- and down-regulation of gene expression.

While our study demonstrates that the establishment of a comprehensive tumour molecular profile on a metastasis is safe, feasible, and compatible with clinical practice in refractory cancer patients, several issues remain to be addressed.

In contrast, photorespiratory mRNA and protein amounts did not decrease in the C3 C4 intermediate species but were mostly equal or even higher than in the C3 species, demonstrating that the establishment of the photorespiratory CO2 pump in the genus Flaveria relies on coordinated changes in the expression of all core photorespiratory enzymes.

Moreover, Orimo demonstrated that the establishment of autocrine signalling loops mediated by transforming growth factor-β and stromal cell-derived factor-1 cytokines is responsible for the induction and maintenance of CAFs' tumour-promoting myofibroblastic ability, thereby indicating the evolution of resident mammary fibroblasts to tumour-promoting CAFs during the course of tumour progression.

The most compelling evidence to demonstrate that idea comes from local unemployment rates: worker productivity went up most in establishments located in areas with the highest unemployment.

This demonstrates that the cohesion establishment factors studied in this experiment contribute to cohesin acetylation during DNA replication, offering a possible explanation for defective sister chromatid cohesion in their absence.