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The in silico deposition results correspond with the in vitro measurements and demonstrate that the engineered microcomposites reach a high lung deposition.
Using an exogenous β-glucosidase, we demonstrate that the engineered strain of P. putida can grow on levoglucosan up to 60 g/L and can also utilize cellobiosan.
Results demonstrate that the engineered Halomonas bluephagenesis TD01 is a suitable industrial strain for large scale production under open non-sterile conditions.
We also present a convenient method to construct mutations and epitope fusions in the cloned type III genes and demonstrate that the engineered substrate protein fusions are recognized by the cloned type III system.
We additionally demonstrate that the engineered biocatalyst can be advantageously used in a SSF process for BDO production from cellulose as the expression of cellodextrinase from a BDO producer augments the insufficient β-glucosidase activities in a commercial cellulase cocktail.
In vitro results demonstrate that the engineered BMSCs have significant suicide effects in the presence of ganciclovir in a dose-dependent manner and can exert a sufficient bystander effect on B16F10 tumor cells in co-culture experiments.
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In vitro platelet-rich clot lysis assay demonstrated that the engineered mutant outperformed the non-manipulated SAK.
Finally, we demonstrated that the engineered K. oxytoca could utilize sugar extracts from a Golenkinia sp. hydrolysate and successfully produces 2,3-BDO.
We demonstrated that the engineered phages are able to target and label abnormal collagens expressed on A549 human lung adenocarcinoma cells after the conjugation with streptavidin-linked fluorescent agents.
Furthermore, we recently demonstrated that the engineered cysteine that increases radiolabelling efficiency is also involved in the coordination of the rhenium tricarbonyl [13].
In the present study, it was demonstrated that the engineered ∆rha1∆lra3 strain can indeed hydrolyze naringin resulting in l-rhamnose accumulation in the medium.
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