Exact(3)
These observations demonstrate that the developmental competence of embryos produced using cryopreserved sperm is equal to or greater than the developmental competence of cryopreserved embryos produced by IVF.
These results demonstrate that the developmental potential of FGF-iPSCs is comparable to that normally exhibited by conventional LIF-dependent ESCs and iPSCs and FGF-iPSCs can functionally contribute to chimera formation.
Together, these results demonstrate that the developmental steps by which wheat grains are filled is correlated with miRNA-mediated gene regulatory networks.
Similar(57)
While the UCP1 gene is absent in the chicken, we have demonstrated that the developmental pathway that generates brown fat in mammals is otherwise intact.
Schipani and colleagues [ 4] first demonstrated that the developmental growth plate was hypoxic, and deletion of HIF-1α led to chondrocyte death coupled with decreased expression of the CDK inhibitor p57, thus strongly suggesting that HIF-1α is essential for chondrocyte survival and growth arrest.
In this study, using assays that detect ROS and ROS-mediated damage, our data demonstrate that the aberrant developmental increases in ROS and ROS-mediated damage, which occur in the Vldlr-/ retina, are inhibited by a single intravitreal injection of nanoceria.
Using pharmacology and dynamic-clamp, we then demonstrate that the two developmental transitions can be precisely reproduced by distinct manipulations of passive and active properties, suggesting heterogeneous timecourses of development of the underlying ion channels.
To demonstrate that AP2C3 expression leads to developmental perturbation of epidermal cells, we have studied the lines with inducible AP2C3 expression under the control of estrogen receptor-regulated expression system (XVE-AP2C3).
These findings demonstrate that the ability to reveal the developmental competence of a cell line depends not only upon the intrinsic state of the cells but also requires a match between the developmental stage of the 'captured' cell line and the host environment: chimaera formation can occur when functionally equivalent cultured cells and host tissue are juxtaposed.
This is not particularly surprising, because our previous work demonstrated that the critical developmental periods for ethanol-induced lethality and developmental delay were separable (McClure et al. 2011).
Initial investigations with a rat model of adolescent nicotine exposure have demonstrated that the vulnerable developmental period for nicotine-induced brain cell damage extends into adolescence.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com