Sentence examples for demonstrate significant alterations in from inspiring English sources

However, despite the large number of samples analysed, we failed to demonstrate significant alterations in serum miR-223 concentrations in critical illness and sepsis.

Non-malignant HRBECs exposed to BPA concentrations, similar to those measured in humans, demonstrate significant alterations in the transcriptional profiles of genesets, including activation of the mammalian target of rapamycin (mTOR) pathway (10).

By high-resolution mass spectrometry we generated a specific metabolite profile for each of the strains and demonstrate significant alterations in the pattern of the production of these secondary metabolites (Fig.  5).

Here, we demonstrate significant alterations in mPFC GS-IR astrocytes already at the age of 1 month, when no Aβ is detected, and decreased GS protein expression manifested from 6 months onwards in 3xTg-AD mice, which could suggest ongoing metabolic pathology.

In the current issue of E-BioMedicine, Brousse et al. (in press) report intriguing data to show that very young asymptomatic SCA infants, whilst still producing very high total levels of HbF, demonstrate significant alterations in reticulocyte membrane protein expression, in association with reticulocytosis.

Findings of the present study demonstrate significant alteration in the locomotor activity and motor coordination as well as oxidative burden (increased lipid peroxidation, nitrite concentration and decreased endogenous antioxidants), mitochondrial enzyme complex (I, II and IV) activities and TNF-α level, in both intrastriatal QA and MA treated animals.

In a rat model of CH [10% O2 between postnatal day (P) 3 and 28], we have demonstrated significant alterations in energy metabolism and excitatory neurotransmission in the developing hippocampus.

At an even deeper level, Dr. Greenfield concludes that the substantial changes in our world that are driven by technology will not only affect our thinking and behavior, but there will also be, as the emerging research is demonstrating, significant alterations in our brains.

As shown in Figure 4, keratinocytes in the skin of BT mice demonstrated significant alterations in the expression of these markers.

Furthermore, histological studies have demonstrated significant alterations in the intestines of constipation-induced animals.

In our model, telemetric recordings demonstrated significant alterations in heart action following laparotomy without pain treatment: HR was increased whereas HRV (IBI, SDNN) was decreased for 24 hours.