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The results suggest that Ag PLGA nanoparticles could demonstrate high efficacy against biofilm infections.
Buccal misoprostol 800 mcg and sublingual misoprostol 400 mcg demonstrate high efficacy and few adverse effects when used with 200 mg mifepristone for medical abortion through 63 days since the last menstrual period (LMP).
Although pre-clinical studies in nonhuman primates demonstrate high efficacy in a realistic motor task with motor cortical recordings, there are many challenges in the clinical translation of even simple tasks and devices.
In the past decade, treatment of RA has improved significantly with the introduction of tumor necrosis factor inhibitors (TNFi), which reportedly demonstrate high efficacy [ 2– 4].
Critically, alectinib is effective for ALK+ NSCLC pts with a history of prior crizotinib treatment [ 8] and ceritinib has been shown to demonstrate high efficacy for pts with ALK+ NSCLC treated with or without prior therapy with crizotinib [ 9].
Thus, beyond the already developed biological strategies, there exists an imperative need to identify alternative RA treatments that demonstrate high efficacy over time in monotherapy, exploit novel therapeutic targets for more effective combination therapies, minimise toxicity and are affordable.
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Supplementation with n-3 PUFA may demonstrate higher efficacy in populations of individuals at high-risk of psychosis and early psychosis than in patients with chronic schizophrenia.
Several reports have indicated that adalimumab or tocilizumab demonstrate higher efficacy in biologic-naïve patients compared to patients with a history of prior biologic use [ 5, 20– 26].
In contrast, albendazole and levamisole demonstrated high efficacy on the majority of farms.
These phytochemicals have demonstrated high efficacy and low adverse effects in multiple in vitro and in vivo studies.
Their results demonstrated high efficacy of gold nanocomposites of these drugs against various Gram-negative and Gram-positive bacteria (Grace and Pandian 2007).
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