Sentence examples for demonstrate defects from inspiring English sources

Taken together, these results demonstrate defects in cell division after UNG2 depletion, consistent with a reduction of CENP-A.

linc Brn1b −/− mice demonstrate defects in proliferation of IPCs.

Furthermore, Dynamin1 knockout mice demonstrate defects in SV endocytosis during strong, but not mild, neuronal activity.

In addition, between 2 to 4 weeks of age they demonstrate defects in retinal outer segment development and photoreceptor apoptosis, resulting from abnormal opsin distribution (Louie et al., 2010), a phenotype associated with NPHP.

We demonstrate defects in platelet spreading and aggregation, intracellular calcium mobilization and dense granule secretion when platelets are pre-treated with the novel FAK inhibitor PF-228 which is, in part, consistent with data obtained from the haematopoietic cell-type specific FAK knockouts.

In the context of pediatric HGGs this is particularly significant, as for pediatric HGGs located in the cerebral hemispheres, approximately half of tumors demonstrate defects in H3K36 methylation acquired by mutations either in H3F3A (G34R/V), IDH1 or SETD2 and seem to primarily affect adolescent/young adult patients [ 20, 66].

In induced cultures, many mitotic cells demonstrated defects in spindle architecture during mitosis.

Detailed analysis of the few surviving mice demonstrated defects in B lymphocyte maturation, aberrant meiosis, and accelerated senescence of mouse embryonic fibroblasts.

Our previous studies had demonstrated defects in both LTP and LTD in the D36 mutants and here we demonstrate that, despite similar PKA delocalization in KO and D36 mice, the electrophysiological phenotypes associated with the D36 mutant are not shared by the KO.

GRHL3 -/- mice demonstrated defects in cell migration.

PMNLs from diabetic patients demonstrated defects in LPS-induced apoptosis.