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Large controlled trials have been required to demonstrate adverse effects of saturated fat on insulin sensitivity, and similar efforts will probably be needed to clarify the effect of TFA on insulin sensitivity.
We demonstrate adverse effects of photopolymerization on viability, proliferation and reentry into the cell cycle of the exposed cells in monolayers, whereas the MSCs retain the ability to differentiate towards the osteogenic lineage.
Finally, animal models may demonstrate adverse effects that humans would not have suffered, and an otherwise good drug will be withdrawn from development.
However, there are no studies that clearly demonstrate adverse effects due to long term use of short acting benzodiazepines in older populations for insomnia.
In contrast to the animal data, evidence from human studies to demonstrate adverse effects of OTA at current dietary exposures, is inadequate.
A number of other studies and re-analyses of published WF toxicity studies on GM crops have claimed to demonstrate adverse effects.
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A List of Hazards Dr. Maloni said aerospace scientists had demonstrated adverse effects of bed rest, like muscle atrophy, bone loss and blood clots.
The 24-hour WHO limit for small particulates is 25 microgrammes per cubic metre of air, though recent studies have demonstrated adverse effects on foetal development at levels well below this.
For example, our own work has demonstrated adverse effects of exposures to endocrine disruptors, particularly when exposure occurs during development -- in the fetus or child -- when our bodies are most vulnerable to environmental insults.
Experiments conducted by Wang et al. demonstrated adverse effects of magnesium deficiency on pregnancy outcome [19].
Previous studies in macaques have demonstrated adverse effects on bone mineral density from the administration of tenofovir.
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