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Comparisons of fixed- (FB) and mobile-bearing (MB) implants have failed to demonstrate a superiority of one design over the other.
Similarly the larger trial [31], where participants were stratified according to previous exposure to neurotoxic ARVs, did not demonstrate a superiority of lamotrigine over placebo for the primary outcome measure (mean improvement in Gracely pain score) in the total cohort or in either stratum.
In conclusion, the present study failed to demonstrate a superiority of DEB-TACE over cTACE in terms of efficacy, safety and, more importantly, 2-year survival.
The study is designed to demonstrate a superiority of ECA compared to standard treatment of each institution for treatment of cetuximab-induced painful rhagades.
However, Soffietti et al.'s outcomes were unable to demonstrate a superiority of the combination of BEV and FTM over either BEV or FTM alone as historical control.
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In vitro experiments demonstrated a superiority of AMSCs for proliferation (6.1 ± 2.3 days vs. 9.0 ± 1.9 days between each passage for BM-MSCs, respectively, P < 0.001).
Furthermore, the new algorithm demonstrates a superiority performance.
No RCT, however, clearly demonstrated a superiority of this association over NSAIDs alone.
A meta-analysis by Rose from 2002 of 177 patients with RHT demonstrated a superiority of thrombolytic therapy over surgical embolectomy (OR for mortality: 2.83, 95% CI 1.04 7.69) and anticoagulation (OR for mortality: 3.03, 95% CI 1.02 3.125) [6].
With the aim to verify the efficacy and safety of sodium valproate in the short-term treatment of MOH, we recently carried out a multicentre study (SAMOHA study) which demonstrated a superiority of the drug compared to placebo after detoxification[1].
ARTS is able to achieve a high accuracy with the area under the ROC curve of 92.77% and 93.44% for genomic DNA chunk sizes of 50 and 500 respectively, demonstrating a superiority to Eponine [7], McPromoter [10] and FirstEF [11].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com