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Our results demonstrate a substantial effect of patch constellation on the exchange of individuals.
Taken together, these results demonstrate a substantial effect of Kv currents on cell survival and proliferation, mainly mediated by IA.
The presented long- and short-term runoff sampling programs in Wisconsin demonstrate a substantial effect from road salt on streamwater quality and aquatic life.
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Although we have demonstrated a substantial effect of HIV infection on biological ageing, estimating the magnitude of the effect is challenging.
Our recent publication from the LowSALT CKD study demonstrated a substantial effect of sodium on increasing BP and proteinuria in Stage III and IV CKD [ 2].
In contrast to other studies demonstrating a substantial effect of fibroblasts [ 60- 66] and fibroblast-conditioned medium [ 67] in stimulating proliferation of cells through paracrine mechanisms [ 3], in our studies we report only a slight increase in proliferation of PMC42-LA in CAF-conditioned medium compared with NMF-conditioned medium.
TCGA consortium have recently published a comprehensive work on ovarian cancer data [ 53] in which they demonstrate a substantial batch effect across Agilent and Affymetrix Human Exon Arrays, which suffer from sever batch effects.
MSCs would seem to demonstrate a substantial beneficial effect on locomotor recovery in a widely-used animal model of traumatic SCI.
We demonstrate a strong effect of genotype.
Still, our results also demonstrate a substantial reduction in Cx43 mRNA levels upon Stat3 inhibition, pointing to a transcriptional effect of Stat3 upon the Cx43 promotor in these NSCLC lines, as previously demonstrated in other cell types [ 28, 40, 41].
In contrast to the above mentioned differential effects of AZA and DAC on cell viability and gene expression, our data demonstrate a substantial overlap of genes demethylated by both drugs.
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