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These studies demonstrate a feedback loop between miRs, corepressors and AR and the imperative role of miRs in AR function in non-cancerous androgen-responsive tissues.
In contrast, statin-insensitive tumor cells demonstrate a feedback response similar to that of normal cells, in which HMGCR is up-regulated; this response may protect these cells from the anticancer effects of statins [ 32].
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The kinematic model demonstrates a feedback formation so that it can be separated into two parts, a linear time-invariant (LTI) element in forward path, and a time-varying gain in feedback.
In particular, the control of upper glycolysis genes by acetylation was shown, demonstrating a feedback control loop from the TCA cycle to glycolysis.
Our data also demonstrate a positive feedback loop between regulation of UCH L1 and β-catenin indicating that UCH L1 affects this major oncogenic pathway [35].
Here we demonstrate a positive feedback between UCH L1 and oncogenic β-catenin/TCF signaling, providing evidence that in transformed cells UCH L1 up-regulates its own expression through β-catenin/TCF-dependent transcription.
In this study, we demonstrate a novel feedback loop in this Rho1-mediated Pkc1-MAPK pathway that involves regulation of Rom2, the guanine nucleotide exchange factor of Rho1, by Mpk1, the end kinase of the pathway.
The results of the present study demonstrate a simple feedback mechanism of re-gulation of mammalian Ero1α involving its primary substrate.
Taken together, this study demonstrate a positive regulatory feedback loop in which ROS mediates hypoxia-induced Mxi1-0 viactivationof of PI3K/AKT/HIF-1α pathway, events that in turn elevate ROS generation and promote hypoxia-induced VEGF expression.
(2011) demonstrate that a feedback loop in a RT pricing regime will achieve efficient decentral coordination.
The simulated data for altered RyR Ca sensitivity demonstrated a regulatory feedback loop that resulted in the same release at lower [Ca]SR.
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