Limbic associated pelvic pain is hypothesized to occur in patients with chronic pelvic pain out of proportion to any demonstrable pathology (hyperalgesia), and with more than one demonstrable pain generator (allodynia), and who are susceptible to development of the syndrome.
In many ways, the pain Ted accumulates from his chilli consumption is more synthetic than the demonstrable pain we can sometimes see him in during his diatribes.
In addition, selective chemical lesion of serotonergic inhibitory neurons in experimentally "inflamed" animals resulted in demonstrable behavioral "pain" hypersensitivity [ 42].The foregoing investigations suggest that disruption of one or more of the elements of the inhibitory system can result in, among other things, the equivalent of central sensitization [ 44].
Nine patients with chronic SUNCT and SUNA with a vascular loop indenting or distorting the trigeminal nerve ipsilaterally to the side of the pain demonstrable on MRI scan were offered MVD of the trigeminal nerve.
The remaining 19 patients (24%) were excluded because they were diagnosed by angiography and/or endomyocardial biopsy as having any of the following: vasospastic angina (n= 6), unstable angina (n= 2), idiopathic dilated cardiomyopathy (DCM; n= 2), Takotsubo cardiomyopathy (n= 1), microvessel angina (n= 2), or chest pain without demonstrable angiographic and histological abnormalities (n= 6).
Much needed is an approach to clinical management and research that allows clinicians to base treatment decisions on a reliable and valid diagnostic strategy leading to treatment choices that result in demonstrable outcomes in terms of pain relief and functional improvement.
Well, admittedly, the Times said "demonstrable," not actually "demonstrated".
However, quantitative BMD loss short of demonstrable fractures has also been associated with back, pelvic pain, as well as with hip pain symptoms [ 5, 10].
To assess the presence of and quantify pelvic pain in a group of women without demonstrable pelvic pathology as confirmed by laparoscopy.
One review suggests that there is a demonstrable impact of specialty accreditation, such as in chest pain management, sleep medicine and trauma management [ 13].
Ehrmann Feldman et al [ 23] defined UEDs as 'having substantial neck and upper limb pain' and Fry [ 24] described the 'overuse (injury) syndrome' as 'those changes brought about in the muscle and joint ligaments from excessive use, causing pain, loss of function, and almost always demonstrable tenderness in the affected structure'.
