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Sacroplasty has demonstrable efficacy and safety; sacral kyphoplasty, however, is rarely reported.
But a surprising story about a product's genesis can be just as important for generating sales as the product's demonstrable efficacy.
Each therapy must have demonstrable efficacy and have minimal risk of side-effects.
A range of interventions have demonstrable efficacy in improving the lives of people experiencing such problems.
Because atomoxetine has demonstrable efficacy, drug-placebo response curve analysis of its performance against placebo was warranted.
Also, dietary therapy restricting phenylalanine and tyrosine is difficult to maintain and has had no demonstrable efficacy in improving the symptoms of alkaptonuria [ 14].
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These observations, along with the demonstrable independent efficacy of HTS and its superior comparative efficacy versus mannitol, argue in favor of HTS as the gold-standard medical therapy for elevated ICP.
The lack of demonstrable clinical efficacy seen with this agent, as well as negative data from other studies of novel agents, was therefore disappointing.
That study also suggested that vaccinated patients had less subsequent risk of HZ, with a demonstrable vaccine efficacy similar to that observed in a large shingles prevention study (45).
Nonetheless, agomelatine's demonstrable acute efficacy is intriguing given its unique pharmacological mode of action and good tolerability, and our findings certainly support further research into compounds possessing melatonergic activity.
Despite demonstrable chemopreventive efficacy in this model, none of these agents, alone or in combination, had any significant impact on the expression of TGF-βs in the mammary ductal epithelium or periductal stroma as determined by immunohistochemistry.
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CEO of Professional Science Editing for Scientists @ prosciediting.com