Exact(4)
Rapid 5' product release and lack of a demonstrable binding site for the 5' product could contribute to the difficulty in establishing the ribozyme-catalyzed reverse reaction (ligation).
We discuss a number of possible reasons for the lack of demonstrable binding of the other peptides below.
Under plasminogen labeling conditions similar to those applied during flow cytometry, we found that surface plasminogen could be detected at plasminogen labeling concentrations as low as 5 µg (100 nM; Fig. 2D), which was ∼10-fold lower than the minimal labeling concentrations required for demonstrable binding by flow cytometry analysis (Fig. 2C).
Class 3, to which αNAC belongs, exhibits no demonstrable binding affinity with long-chain ubiquitin in yeast (Egd2 is homologue of αNAC in yeast).
Similar(56)
Although TPP1 itself has no demonstrable DNA binding activity, it enhances the interaction of POT1 with telomere ssDNA (27).
SP-A was also found to disturb the host inflammatory response to IAV infection in mouse models without directly influencing viral growth and spread, and even without demonstrable viral binding, at least when the virus was resistant to neutralization by SP-D [ 9].
In keeping with the previous findings that LILRB1 preferentially binds to HLA-G dimers, no binding was demonstrable with JEG-3 cells that mainly displayed conventional monomeric HLA-G.
Furthermore, the lack of a demonstrable effect on daunorubicin binding to the plasma membrane by modulators points to transport mechanisms which do not utilise specific drug binding to the plasma membrane.
The first demonstrable event upon NGF binding to TrkA is autophosphorylation of the receptor.
Similar affinity and binding capacity was demonstrable in normal mucosal samples.
Using the assay, binding proteins were demonstrable in all of 100 tumour cytosols.
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