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Despite the fact that we have presented a simplified model without recombination or migration, our results provide mathematical formulas that allow us to estimate imputation accuracy for a variety of demographic and sampling scenarios.
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Descriptive statistics were generated for demographic and sample characteristics, actigraphic assessments, and clinical scales.
All patient samples used in this study were gathered from previous studies, and their corresponding patient demographic and sample collection information is described in detail elsewhere [ 9, 20].
Demographic and sample characteristics are summarised in table 2. The physician list was inadequate for the purpose of administering the survey as indicated by the difference between our start-up count of 18 642 and the final adjusted count of 10 327.
A description of the Stanley Brain Collection and more detailed demographics and samples' quality were previously reported [35].
Demographic and tissue sampling data are listed in Table 1.
Demographic and socioeconomic sample estimates were weighted for age, sex and place of residence in accordance with the respective strata from the sampling frame [ 22].
Parasite DNA was retrieved from dried blood spots from 7 Demographic and Health Survey sample clusters in the DRC.
Demographic and standardized sample characteristics were non-normally distributed and summarized using median and 25th to 75th inter-quartile ranges (IQR; continuous data) and Ns (percentages; categorical data).
Demographic information and sample characteristics are summarised in table 1. Overall the median (IQR) CRP concentration of the sample cohort was 3.6 (IQR 1.0 12.7) mg/L.
Thus the applicability of the results from our simulation study is fundamentally limited by our range of demographic models and sample sizes simulated.
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