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With many experimental drugs, the agency demands trials with thousands of patients, while for cancer, it has accepted studies with a few dozen.
Detection of modest but worthwhile treatment effects in randomized controlled trials (RCTs) demands trials of large sample size.
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Students have been taught that A's and perfect test scores are the goal, while computer science demands trial, error and failure to achieve success.
There is recognition of the additional demands trial participation brings but this is viewed as worthwhile as the outcome can be service improvement.
Yarnold, however, had speed and power and, most of all, an obvious steely calm which translated well in the demanding trials.
Unless some compromise can be found, legal experts say, a major step in international law will be taken without United States participation, even though Americans have been at the forefront of demanding trials for leaders like Pol Pot and Saddam Hussein.
It had been given the name "the Day of Purge," and it had been called to demand trials for Mubarak and other leading members of the old regime suspected of corruption.
They demand trials that have shown the effectiveness of drugs on hard end points – their clinical usefulness".
Incompatible, demanding trials evoke response conflict, which is thought to generate increased cognitive control on subsequent trials (Botvinick et al., 2001).
The authors found that lesioned monkeys performed normally in shape or size oddity discriminations, but performed worse than control monkeys in perceptually demanding trials with e.g. degraded stimuli (see also Buckley and Gaffan, 1998; Bussey et al., 2002, 2003, 2005).
Moreover, in line with this pattern of brain activation and fitting previous research [ Bijleveld et al., 2012b], there was also an effect of supraliminal reward cues on performance: high-value (vs. low-value) rewards facilitated performance, specifically on demanding trials.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com