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The development of in vitro adipose tissue constructs is highly desired to cope with the increased demand for substitutes to replace damaged soft tissue after high graded burns, deformities or tumor removal.
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Environmental problems, depletion of fossil fuel and industrialization inevitably highlight the demand for substituting a viable and renewable energy resource.
However, whenever a product is no longer available, true demand may differ from registered bookings, thus inducing a negative bias in the estimation figures, as well as an artificial increase in demand for substitute products.
Every year, a frightening increase in the number of bone injuries is estimated to continue around the globe, which leads to high demand for bone substitutes [2].
NORML spokesperson Chris Fowley said that as long as cannabis remains illegal, there will always be demand for synthetic substitutes.
The demand for bone substitutes is more than 2.5 million units in this category of indications alone.
Note that in all numerical examples the number of delisted items always corresponds to the difference between N and S, which shows that it is always more profitable to list an item than delisting it and using the respective space for additional OOA demand of substitutes.
The high toxicity of Cr VI) compounds, used in the established chromium electroplating process, and the strengthening of safety and environmental regulations demand a search for substitutes for chromium or at least a change to less toxic chromium III) compounds.
An increased demand for soft-tissue substitutes has impelled the development of an in vitro adipose tissue.
Since both options are highly limited by the age of the donors/recipients and their availability, the demand for synthetic bone substitutes has been increasing as an alternative source for bone regeneration.
New technology might on the other hand also decrease demand for labor by substituting large number of low-skilled employees with fewer high-skilled employees or by substituting capital for labor.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com